My experience is limited with cables, but the only cable that I've heard a significant difference with was a W Audio power cord that I picked up for about $40 on Amazon. The W Audio power cord made a significant difference for my Pathos amplifier. As a result of that experience, I have ordered Audioquest Chicago interconnects to go between my DAC and amplifier to see if I can hear a difference compared to the Blue Jeans Cable LC-1 interconnects that I currently have.
I'm still working on my theory for why I heard a significant difference with the W Audio power cord on my amplifier and maybe with my power conditioner, but not necessarily with my DAC or SACD player. I suspect that the W Audio power cable rejects noise better and the amplifier is the most sensitive to noise.
Part of why I'm willing to try the Audioquest interconnects is that the power cord brought out some micro details that makes me wonder if my system is now at a level where I might hear a difference that I couldn't hear before.
I'd suggest trying a W Audio power cable and seeing if it makes a difference in your system. If it eliminates some noise I think it'll allow you to hear things that you otherwise couldn't when evaluating other potential upgrades.
What speakers do you have?