I suspect that the difference between the Set and the Megaschino is both the amount of distortion and the profile of the distortion with the SET amp having more 2nd and 3rd harmonic giving it a tonal difference. In my case, with the 2Cherry, I've never owned an amp that was as clear, tonally correct and presented music in a life like way.
I pretty much change my system up every 2-3 years...I guess because the gear is as much fun for me as the sound. Most of the time, I sell the current piece to make space for the next piece, although lately I've just given gear to my son as his interest in the hobby seems to be growing.
I've got my eye on a couple of amps and as such, will sell the 2Cherry...and usually there is an overlap of the old with the new so a comparison may be possible.