@bigwave1 See you're using modded mac mini. Have you bridged firewire port as second ethernet port? This port will connect direct to Meitner. Will be superior to using the single ethernet port with switch. Also, which power supply using with mini, this makes large difference as well, I use Uptone JS2 with my mini. Also what have you done to optimize operating system? Get third party app wipe conversion, disable as many processes as possible. Disable system integrity protection, major upgrade, Get fastest processor, I7 better than I5, run PCIe ssd vs sata.
Get rid of any usb or conversion or rendering prior to Meitner, don't complicate things here. Mini direct out to Meitner, Power cords important, power conditioning as well. Weak links are weak links, with streaming so many possible weak links!