Do speaker cables really make a difference ?

@dweller you can multiply it by another 100 -- make it 10,000 as in my case, but the fact will remain the fact -- you won’t know which one sounded better on which wire and on which record $10k or $10.

@whipsaw +1 on Audience. I also use AU24SX speaker cables terminated with rhodium plated spades that replaced a much thicker Purist Aqueous 20th Anniversary which was a very good cable. Thickness of speaker cables is irrelevant if the materials used, design and implementation are done right. 

@rsa

Depending on your system and your ears, yes, you can hear a difference. You don’t have to spend a fortune. Many people are very happy with Blue Jean Cables.  As other correctly say, the size of conductor, which equates to a low resistance, is important.  Capacitance is not as big an issue in speaker cables as it is for line level interconnects.    

yes, but a much smaller amount than room acoustics. 

Often high end cables make things noticeably worse on one way or another.  My suggestion is to try some Mogami cables.  Inexpensive, great bass.

Not really, if you have decent cables in the first place.  ELAC has decent cables, for example, and that's all you'd need.  There are other relatively inexpensive and perfectly capable cables, like Blue Jeans as another has suggested.

If you don't like how your system sounds, it's not likely the fault of the cables... it's more likely you are dissatisfied with the speakers, the amp-speaker pairing, or, and here's the big one, how your system integrates into the room itself.