This is a really interesting thread. I recently decided to try a tube pre (Zesto Leto) in my set up. It pairs with my balanced DAC (MHDT Pagoda), SS Amp (Krell XD Duo), Alta Audio Alec’s and the streaming is handled by a Auralic Aries G1 streamer.
My other Pre is a Krell Illusions ii.
When I introduced the Tube Pre, found the synergy / match on again / Voltage was off - as noted on this thread some Balanced DAC’s come out hot and that’s the case with my DAC. Without any adjustment I barely have to move the volume on the Pre. What this causes is similar results to having too low a gain, I’ve got a hum and the highs overpower the mid’s / bass. When I put a attenuator into the mix at the input stage of the Amp (- 10 DB) dramatically lowered the hum and balanced off the sound. Even at - 10 DB it’s still a bit hot, can’t take the volume knob above a quarter turn. I really like the sound of the tubes on the front end so my solution long term is having a custom box built that will allow for 3 different setting on voltage and a bypass setting. I could send the Pre in to Zesto and have the gain adjusted but then if I decide to switch amps or my DAC I may have mismatch the other way. This set up will allow some flexibility.
The moral of my story, findings is that the synergy / marriage of the pre and amp as it relates to gain / voltage is important. Can have a significant impact on sound quality and the noise floor. Most will point toward issues when something in the chain is too low but if too high, causes issues as well.
Happy Holidays and Good luck on your Audio Journey!