We have two breaker boxes, the original, which is fully loaded with breakers, and a second added later that is closer to the street that has a few breakers in it. I ran 125 feet of 8-gauge multi-strand from the stereo location in the living room to that panel with a 20 amp breaker and put a 20/30 amp outlet on it inside my entertainment center. (My surge protector has a 20/30 amp plug.)
From the 20/30 amp outlet I ran the 8-gauge to a pair of hospital-grade outlets located just outside the entertainment center. The run is continuous and there are NO breaks in the lines between the various outlets. There is also a big ferrite bead over the wire where it comes out of the panel. Even the hospital grade outlets accepted the 8-gauge wire without problem.
This had the effect of removing "high-end hash" from my Yamaha Universal Player. It did less for my Oppo95, and I attribute this to a better power supply in the Oppo.