I have upgraded phono cables in nice but non-audiophile turntables a couple times. I could never hear a difference. The last was in an AR turntable with a pretty good cartrige.
I am a big advocate of carefully choosing interconnects, cables, and power cords, and have done so multiple times over the last fifty years as I have built and upgraded my system.
That has been my experience. Yours could be different. It will also be depended on how good the rest of your system is.