@peareye Given your clarification that you predominantly listen to YT off your MacBook I agree that a USB based connection is what you'll need to use so considering DDCs to help optimise it makes sense.
Reason being, as notwithstanding my preference for the sonics of the R26 LAN input/renderer, the R26 doesn't support any LAN streaming protocol I'm aware of that'd support YT audio. Happy to be corrected here if there's a workaround way to pipe it via UPnP but doubt it'd be easy or ideal if there's video lipsync considerations.
I also listen to and watch a bit of YT, in my case via my TV, using its optical out. I feed this to an Ifi s/pdif iPurifier 2 reclocker (a DDC) then into the R26 coax digital input. This sounds much better than going direct into the R26 optical input which doesn't do any reclocking of the jittery signal from the TV (so is thin and glare-y) and slightly better than going USB direct from my Mac Mini into my U18 DDC but not as good as the LAN for equivalent non-YT music.
That said having recently experienced a substantial improvement from inserting the Holo Audio Titanis USB regenerator/ galvanic isolator in between the Mac and the U18 I reckon that would likely now better the TV/Ifi chain for YT content. I must try it.
Re clock cables the one you referred to looks to be an HDMI cable which could be used to carry i2S signal from a DDC to the R26, but for the external clock connections (ideally to both DDC and R26 so they're synchronized) you need a BNC-BNC terminated 50 ohm coaxial cable like the Gustard C2 or LMR400.