As for minuses I can give you an example. If you listen to violins in an orchestra in FLAC they sound rich, harmonious, they ebb and swell with the tempo, its wonderful. But they sound like a group of violins, not individual violins.
When I listen to a good MQA master I hear more of the individual violins standing out from each other while playing together as a group. If you weren’t able to compare you might never notice, but once you hear the difference you notice it when it isn’t present. I find 24/96 PCM to offer "more" of everything but still doesn’t get that rich sound of each individual instrument the way I get with MQA.
You are describing my exact experiences with quad DSD vs PCM (24/96 and greater).