One man's datapoint.
Hsu VTF2 Mark IV subwoofer. (Out of production.)
In TV system: one sub off to one side opposite main speakers but not in corner..
In audio system: four subs behind main speakers.
No difference between one sub and four.
Subs make your main speakers sound better because they don't have to work as hard with the sub handling low bass duties.
This Hsu sub has two ports which I have plugged with the foam plugs that come with the sub. Less bass but tighter compared to leaving the ports open.