I have been more loyal to a wire type used for the Signal Path, more so than a Cable construction, even though pure copper connectors used on both cable ends and chassis mounted connections is today seen as a mandatory requirement.
I will state with conviction, swapping a Copper Wire to a Silver Wire, will usually create a sonic that is undeniably different. Depending on the wire type, the differences can be worlds apart, I have experienced Silver Wire, that had to be removed with immediacy, as it was such an unattractive sonic in the system it was used, on the same note I used a Silver Cable in favour of Copper for multiple years, until I discovered PC Tripe C Wire.
I have found experiencing the same wire used in a cable, where a cable is produced at differing lengths, between 0.5mtr - 5mtr. When undergoing a A/B comparison, where the 5mtr cable works along with a device placed in the system, that can use the shortest cable, there are subtle differences to the sonic, that are able to be detected between these cable lengths. Usually a frequency can be controlled in how the projection is being perceived, using this method. No need trying anything like this if a 5mtr Cable is not required within the system.
One of the biggest changes to a sonic outside of changing a wire type, was when what had become a very untidy mess behind the system was given a period of my time to have the cables organised, separated and avoid crossing over where possible, the organised Cables brought a sonic that was immediately noticeable for being more attractive.