The heart of your system could be as few as 2 or 3 major components.
* integrated streamer/DAC/preamp. Consider offerings from Lumin, Matrix Audio, T+A, NAD, For the OP’s situation, I might lean toward the Lumin P1.
* Kef LS60 active speakers
OR
Kef LS50 Meta speakers + Benchmark AHB2 power Amp + Rythmic F12G sub
The Lumin P1 new ($10K) and KEF LS60 new (~$7K) would break your budget. May be hard to find used. The Matrix Element X2 or X2 Pure offer feature sets similar to the Lumin P1, but for thousands less. Actually, I might prefer the X2 Pure new to the P1 used, especially considering warranty/return rights if you are unable to audition in a shop before buying.