"Significant" ? I think some folks should look up the word in the dictionary. Different? Yes, but tiny, tiny, tiny unless you are letting your belief system modify what you hear vs. the actual sound.
What constitutes "significant" is mostly subjective. What you insist is that others accept your definition of what's important, and what's not. If I happen to not agree with you, it's the fault of my belief system? What a load of nonsense.
Just because "believers" will accuse me again of saying ...
You see "believers" and magic and pixie dust everywhere you turn, it seems. That says a lot about you.