Depends on the quality of the streamer in my experience. I currently use a BlueSound Node 130 (With LHY LPS) with various USB cables, to a Denafrips Iris DDC, and then I2S Audioquest Vodka 48 8K/10K HDMI cable to a Denafrips Pontus II DAC. The sound improvement of this stack is impressive for such a low cost combination, with each upgraded component adding to the SQ.
That said, I've borrowed a couple of streamers (Aurender N10 and N200) that were amazing and much better than my set up, and I suspect that the iris is not needed....but those are $6,000 streamers or there abouts. I am currently saving the funds to upgrade to the usual suspect streamers (Innuous/Lumin/Aurender)