@mcanaday -- "Seems weird that would lead to NO SOUND rather than hissing"
Hissing usually happens due to a tube's age as it approachs the end of its useful power-on lifespan. That can range from 1,500 or 2,000 hours for a power output tube to many multiples of those figures for tubes used in preamp stages.
Obviously, a tube can fail in other ways, sometimes quickly, that completely interrupts the circuit. Sounds like this may be your situation.
Hope you find the replacement tube fixes your problem.