My only experience in turning a cable 180 degrees, the only one I have done and it was an error, not an experiment, was using Star Quad DIY cables, of which I always make up and use. I attach the shield at the input end and cut it back and tuck it into the jacket at the receiving end, the idea being any noise picked up goes back to ground at the equipment up instead of down the chain of gear. That made sense when it was suggested to me and what I always practice and never have noticeable noise in my systems. I cannot say I ever noticed a change swapping it back to the right orientation but that might of been so, it has been well over 20 years ago.
If a cable is specifically designed to go one way then I would just use it as such, if not I would have to hear it in person to agree it made a difference which ever way it was installed. Not saying I do not believe it would or not, I just do not know.