My experiences for optimizing Roon Sound:
-I am a lifetime Roon subscriber for some time and love the features.
-avoid all DSP as much as possible as to me it adds noise. You don't hear noise per say, but it destroys the soundstage and ambiance.
-for critical listening only run one Roon endpoint at a time. This is easily heard if you turn other endpoints on and off while critically listening.
-for the above reason, I have moved away from having 4 Roon endpoints in my home. Now my bedroom and master bathroom (hardly critical areas) are now the new Sonos ERA 300 speakers which are really good. They are extremely stable and sound just fine in my bathroom and bedroom. It is easy to add playlists from Qobuz onto your Sonos system. The Sonos ARC is also excellent, better than my Marantz AVR with a passive soundbar.
-I am not saying Roon sounds better than Innuos Sense or Aurender Conductor. But the features, ease of use and music discovery of Roon are better and it still can sound amazing.
-I would not buy a high end streamer that is not Roon Certified as an endpoint. (come on Aurender!!!).
-the main place I NEEDED DSP was the master bathroom. the Sonos ERA 300 easily adjusts its frequency response to the glass and tile environment.