The cables question is ill-formed.
I would agree that there is a difference between the worst and the best. There are many physical properties to consider: Resistance; Capacitance; Inductance; Dielectric Absorption; RF rejection; connection integrity..
So yes, there are differences based on physical principles, and understood to physics. Are they important? Yes - but system dependent. If you seek transparency, then that's easy - decent connectors and quality cabling like Canare will set you up nicely, and be somewhat better than lamp cord.
But, for example, if you have an over-bright system, then a high resistance, high capacitance, high inductance, high DA cable may correct it to the point of listenability. Of course, you might do lots better with better components, but cables do make a difference. They are just the worst way to do it. IMO.