I wouldn’t call them scientific, but they do have their own sound in my mind. One of the best "scientific" attributes of Magico is the power response. The extremely wide and even dispersion makes these speakers throw an excellent image to a wide listening area.
At the same time, this means they need more room around them. Putting them in a cramped room is an absolute waste of money, IMHO, even for their smallest models.
From a tonal perspective, I find glass smooth but also a little cool on the top and (and I know everyone disagrees) I find them a little chesty. Female voices and piano registers to me have some extra resonance there.
Fatiguing though? Not when driven by excellent tube pres, which is the only way I’ve heard them.