Is it possible to have too much/too many filters/tweaks?

It’s very possible to get tweaks wrong rather than right. The actual number is irrelevant. Best approach: Keep tweaking as needed. Focus on high value tweaks like proper setup and component matching, DSP, room treatments, placement, shielding from external sources of noise. The actual gear used should matter less the better you are at “tweaking” effectively. Except in your head, of course.

If your tweaks consist of buying a lot of expensive and esoteric gadgets and devices you are not on the happy path most likely.  Unless buying stuff alone makes you happy.  That’s ok too. As long as it truly makes you happy. Have at it!

Yes.  If something actually does alter the sound, it has the capacity to alter the sound in a way you might not like.  It is not always the case that certain things one seeks to reduce, such as resonance, is bad at any level such that less is an improvement.  One can go too far in that direction.  I heard a demonstration of various platforms made by a particular company that were placed under a CD player.  The lowest level platform did a very good job of improving the sound as compared to the stock shelf that came with the equipment rack.  The next level up platform made a small improvement over the company's entry level platform.  The all out maximum resonance draining platform was simply too much--the sound became thin, analytical and harmonically thread bare; even the manufacturers representative agreed that it was too much in this particular case.

Yes, I have been through countless "tweaks", most did nothing, some did maybe something +/-, and a few are great! And mixing them can be a crapshoot.

I guess that is why you should try them if interested, you just never know. There are some very creative minds.

ozzy

Time to mention the #1 Class A tweak: Cup your hands behind your ears. Instant Class A amp sound! Very energy efficient!  How did they do that?

Someone once sold ear extenders that gave the wearer Dumbo ears that supposedly improved the listening experience.  While it may have improved the sound, it probably did not help with getting a second date.