I tried Ifi ZS which has isolated asynchronous usb with R26 already and it does not resolve the issue. MXN10 sounds better (than Ifi) so I stay with it.
Maybe Audirvana sounds better than MConnect, but I doubt it can make that big of a difference. The reason I call it awful (sorry for the strong wording; how about "at best average" used by the other gentelman here) is that it costs over $1k more yet sounds worse than the MXN10, iFi Zen Stream, and Wiim. Both my primary (humble) and secondary (still humble) systems can easily reveal the sound quality disparity.