I have a mix of quality cables most of which I have found used for about 50% of retail. I have bought some new but never at suggested retail prices. I have a mix of Jorma, Acoustic Zen, Shunyata, Nordost, Zavfino, Silversmith Fidelium. SOtm, DR Acoustics. No rhyme or reason as to a procedure, but if I see a good deal on a cable I try it. At times I have used something I thought was a downgrade, but most times after swapping a cable that was worth $500 for something that retailed for $1000 it sounded better. And swapping out a $1000 cable for a $2500 cable was also an improvement. Go figure. I will add my Silversmith Fidelium's replaced a speaker cable that retails for 3 times what they did, so it not always the higher priced items win. I am happy with the sound of the system but I will probably always tweak away with different cables to see how the sound gets "tweaked". Like experienced audiophiles stated above, you don't have a clue until you try it yourself.
Don't know what a full loom sounds like. Maybe I will try a full-loom of something someday, but for an example the Tyr2 XLR I bought that I do think sounds wonderful between my DAC and pre amp, if I were to pop down to the dealer and "full loom" my system with this cable here is what it would cost me in Canadian retail prices:
Nordost Tyr2 2m speaker cable: $9965
Nordost Tyr2 1m XLR: $3959 x 3 = $11877
Nordost Tyr2 digital: $2300
Nordost Heimdall ethernet (no Tyr2): $990
Nordost Tyr2 1m Power Cord: $4421 x 5 = $22105
So I would walk into a dealer and hand him a grand total of $47237 plus taxes of $5668 = $52905?
I can't do this. And if I could I wouldn't want to.
But also waiting until I find all the pieces above at a used price could take years. Also I love what my Shunyata Sigma V2 power cable did in my system, so maybe I will go all Shunyata? Choices choices.