System assessment...

Just retired...I have the time and interest to consider system upgrades. Although I have some very nice gear, I'm not sure about the synergy of the system as a whole. My system has been assembled over many years, gradualy making upgrades and improvements. Sadly, all changes have been done through thorough research, and educated risk taking.. I don't have access to a brick and mortar shop, a 5 hour drive to Chicago or Twin Cities... 

I'm looking for opinions regarding my system. Do I have components that don't necessarily complement each other based upon others experience and opinions. I'm open to stepping back and rethinking the entire system if necessary. Below is a list of my components and speakers. 

Aestthetix, Mimas , integrated w/DAC 

Jay;s Audio M2 transport

VPI Prime w/ Shyla cart

Manley Chinook, Upscale Audio Special, phono

KEF ref. 1 (not Meta)

(2) REL SHO S/3 subs

Silversmith Fidelium speaker cables

My other cables are a hodgepodge  collection of  budget and midrange quality.

Any observations?

Thanks.