Yes, you can, but it is rather approximate. Use your meter on the resistance scale (ohms), but understand that impedance is not resistance and the impedance will generally be noticeably higher than the resistance measurement.
Sorry that math is complicated, but if using two drivers with with the same impedances, just divide by two. So two 8 ohm drivers in parallel will have a net impedance of 4 ohms, and two 4 ohm drivers in parallel will have a net impedance of 2 ohms. Hope that helps.