A stereo cartridge is sensitive to vertical modulation of the groove. A mono record has only horizontal groove modulation, and whatever vertical movement occurs (and this includes turntable rumble) is pure noise, and you don't want it. It is essential to remove sensitivity to vertical modulation by jumpering the two channels together, or using the MONO switch on your preamp (if it has one).
Improved results may also come from using a different (larger) stylus, and these are available for some stereo cartridges.