If you ask a dozen different people you will get a dozen different, and equally ethusiastic, recomendations. That tells us something. Are we listening.
I have about as 'hi-end' a system as is possible, and use Radio Shack Megawire for speakers, and Cobalt Cable interconnects (after several Radio Shack pairs were found to have loose connections ---bad weld, or something).
I traded in $3,000 worth of wire fearing it would be an audio train wreck, but found the system just sounded more real.
The different cables can sound different, but then any 'sound' that any component contributes to the recorded signal from the source material is *distortion*.
The best you can say about any component is, 'I cannot hear it', it is therefore 'transparent'. The 'connoisseurs of coloration' who use their system to further mix the music beyond the damage the producers have already done with their room size 1/4 million dollar mixing console toy, notwithstanding.
If you want to see those self proclaimed 'connoisseurs' run and hide, just say, 'blind test'. They know what it means, and fear it like Dracula fears light.
Anyone can use reference quality earphones (Shure ER2 $100) to hear the turth of a recording, then compare it to the system/setup to see what the effects are that deter from 'true to the original' in the electronic playback of music.