Kijanki, yes, I think I can. The purity of metal has a lot to do with 'diode effects' in the material. The idea is that strands of wire do not conduct completely linearly- they are affected by diode junctions that exist between them.
However these diode junctions are not very profound or robust. They would only be detectable (if you will pardon the pun) if you had very low currents in the cable.
Well my friends, this will be the case with most single-ended connections, and for that matter any connection of high impedance.
OTOH, if we are using a balanced system *that conforms to the balanced standard* then there *will* be significant currents, and any primitive diode junctions will be of no account.
Now I should point something out. If anyone tells you that they have more than 99.99% purity of metals in the wire, they are likely pulling your leg. Oxidation makes it virtually impossible to exceed this figure!
Additionally, OFC (99.99% pure copper) was *not* developed for audiophiles, it was developed for alternators and generators because it is more flexible. However, a few weeks after extrusion into the insulation, there will have been enough oxygen contamination of OFC so that, other than flexibility, it will have about the same characteristics and purity as regular ETP copper.