I left the enzymatic on a few different LPs for 1/2 hour every day for about 6 weeks. If the enzymatic began to dry, I added more. During, and at the end of the testing, I played all the LPs, and found no damage or degradation under illuminated microscopy. I continue to play these LPs (some 4 months post first application), and continue to find no damage. Because of this regimen, enzymatic was left on the LPs for a total of some 1,200 minutes (20 hours) ... certainly many, many multiples of the amount of time that should ever be necessary: unless you subsequently get grease or fingerprints on your LPs, I don't think you'll need to use the enzymatic more than once.
I did not get as much grunge off my LPs as Jphii reports ... which did cause me some concern. However, nearly all of the LPs had been previously cleaned with the cleaner formula, variations of which I have used for a few years now. (More recently, I played with formulation of the cleaner formula to find the combination which seemed to be the best solvent for the enzymatic).
While I let the enzymatic sit on my vinyl for the noted extended periods (1/2 hour at a time), I can't say I recommend that others do so as well. I only know what my results were, and that based on my LPs being fine, after leaving the enzymatic on 1/2 hour x 6 weeks, I have a high level of confidence that the enzymatic is safe when left on for much shorter durations.
BTW, the enzymatic I sourced is supplied containers made of HDPE (High Density Polyethylene) ... which is a variety of vinyl, and I personally use HDPE squeeze bottles to apply both cleaner and enzymatic formulas to the LPs I am cleaning. Now, I am not a chemist, but it seems to me that the chemical structure of proteins and vinyl are very different. Proteins are made of amino acids. Vinyl is made from ethylene (derived from natural gas or petroleum) and chlorine (derived from salt). Maybe someone with more chemistry knowledge than I could jump in an explain the structural differences.
Tomorrow I'll find out more about making ultra-pure water, and report back.
Best regards,
Paul