What's your favorite remake of a song

These made extreme hits out of previously obscure songs

Black Eyed Peas - Where is the love
Soft Cell - Tainted Love
All Along the watchtower - Jimi Hendrix
Der Kommissar - After the Fire
Hound Dog - Elvis Presley
Please don't let me be misunderstood - The Animals
Red Red Wine - UB40
Shake rattle and roll - Bill Haley's Comets

Sonny and Cher's "I've got you, babe...", sung amazingly well by Patricia Barber.

I just saw Gretchen Wilson and Alice in Chains do Heart's Barracuda but Nancy Wilson was playing too. I actually think that Gretchen Wilson sang it better.

Yes, lots o' good stuff already mentioned.

One not listed yet is "You Really Got Me" by the Kinks.
Nicely updated by Van Halen.
But the version I really enjoy is by Oingo Boingo!

I will second the Cowboy Junkies "Thunder Road" and add:

Shonen Knife: "Top of the World" (Carpenters)
Bob Dylan/Tiny Tim: "I've Got You Babe" (Sonny and Cher)
Be Good Tanyas: "Waiting Around to Die" (Townes Van Zandt)
William Shatner: "Mr. Tambourine Man" (Dylan, Byrds)
Nazareth: "Love Hurts" (Roy Orbison)
Persuations: "The Wanderer" (U2)
Ike and Tina Turner: "Proud Mary" (John Fogerty/Credence)
Tom Waits: "Hi Ho, Hi Ho" (from Seven Dwarfs)
Aretha Franklin: "Jumpin Jack Flash" (Rolling Stones)
Sebastian Cabot: "It Aint Me Babe" (Dylan)