45 degree placement in squarish room?

Diagonal placement works quite well in small rooms. Here is a good read on it:

http://www.decware.com/paper14.htm

Also, at the recent Bay area audio show one of the best rooms IMO was DeHavalind, using a diagonal set-up. Roger Sanders uses one too at shows where he exhibits.

I have an asymmetrical though not strictly 45 degree configuration I use with my OHM 100S3s in a small 12X12 room that sounds about as good as it gets.

That's great to hear, thanks!
Do they need to be equal distance from the shared corner, and respective side walls? play by ear or measure?
thanks again! it sounds so good I'm afraid to move em...
(don't worry, I've got friends coming over, skeptical ones, who will do debunking this weekend.)

They don't need to be equidistant from the shared corner. Using this set-up you can be more flexible in how you place the speakers. Use your ears to judge.

My room is not small at 17 x 25 but I have used a diagonal set up for years with excellent results, Far better than any symetrical set up I have ever tried in this room. The speakers are not even close to equidistant from any wall surface. My left speaker is several feet to the left of the corner and the right speaker is about 9 feet out of the left corner along the wall. Don't let anyone tell you what you should or shouldn't like. This set up works extremely well.