I loved my McIntosh MC-2100. I had mine for about 2 years, and I found it to be a fantastic vintage amp that has a nice tube-like sound without being round or lumpy. It still has the control of a solid state amp, but it's not as etched sounding as the solid states they started making just a few years later.
I have never driven Vandersteens, but I used my 2100 to drive a pair of Thiel 2.2 speakers, and they are notorious for wanting loads of quality power. I can say that the Mac drove them with aplomb, and would have no qualms recommending this amp to anyone. It won't win any beauty competitions, but at $400 if it's in good condition you should jump on it.
- Dusty