Solid state amp vs tube amps

It depends on the specific amps, the speakers and system being used, and several other variables, but in general, yes....there’s a notable difference in how they sound.  The better the system, the easier the differences are to hear.

+1 knotscott

There are differences that are more easily detected, as stated above, the more resolving your system is.  In your system u have to figure out which general amplifier type u like better.  Complicating matters is that within an amplifier type there will be discernable differences in sound signature.  I find that I mostly gravitate toward high powered hybrid and solid state amps driven by a tube preamp.  I have a modest powered strong performing class d amp that's also a honey.  You just have to listen, experiment and experiment more.  You can listen to reviewers, at least some of them.  However, I have had gear that once listened to, I could not get my arms around what had been written in a respectable Audio mag.  I have though found an alignment with Terry London's listening preferences- not completely but mostly.

All things being the same, they will sound the same.

In general, yes… very much. Solid state tend to be much quicker but very easily run out of power. The often have much less mid-range bloom and rhythm and pace… resulting a much less musical sound. In general tubed amps will sound much more powerful and natural. I had top of the line powerful solid state amps for decades. Once I got a tube amp, I will never go back to a solid state.