The biggest, and I think consistent difference between good quality solid state and tube amplification is in slam. To me, after decades with high current solid state amplification, appreciated slam… which tends to be much greater in solid state. The midrange tends to be a tad leaner and the bass transients really fast… this gives the characteristic slap of fast bass. But, I have never heard this in live performance… amplified or acoustical. High quality tubed amplification tends to have a more fully fleshed out midrange and upper bass and the bass is finely nuanced… but the transient rise is slower… which is actually what I hear in live venues.
I get why one would like either… but the moment I heard the later (tubed)… the former was out the door for me. Did I loose something? Yes… but for me, what I gained was many times greater than what I lost.