Defense in depth: Absolutely begin with a whole house surgeprotector. It is the cheapest insurance known for everything electric in your home, especially if you lie in thunderstorm prone areas. If you have sub-panels, but one in their as well. Next is your point-of-use devices. Whether you decide to go with a simple quality suege protector, more elaborate power conditioner, or all the way to a battery power generator is up to you and your circumstances.
I would also check out Ting - www.tingfire.com - an electrical arc fault detector. State Farm just sent me one for free. Apparently they can detect 80% of all electrical fires before ignition. I get a monthly email report showing voltage fluctuations, outages, brown outs, and voltage spikes, which is kinda fascinating in a nerdy quasi-paranoid way. But the reassuring note that no faults were found does deliver some peace of mind. They're $99 with a year of monitoring, and include a pretty cool app, if your insurance company won't freebie one.