The two factors that are frequently ignored in the streamer space, beyond the 1's and 0's, are noise and jitter. These are real factors in hardware design and in the end audio quality. Especially jitter. It is undeniable that the clocking of the signal is critical to delivering good, focused sound.
If you understand that then you should also understand that the product of noise and jitter is distortion. And the levels of distortion that are audible can be measured and have been known for many decades. And almost all digital devices are below those distortion levels. No one disputes that humans can't hear 50kHz. Why do people dispute that they can hear inaudible distortion?