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I also share my office with my listening room--a sort of man cave built above my garage. Here are my 2 cents after trying different speakers and amps over the last few years.

1) Nail down the speaker you like and listen to it in your room to make sure it's right. I had Harbeth SHL5s and, on a whim, bought some B&W 803Ds. Bad idea. Overwhelmed the room and my current integrated didn't drive them well. I currently have Dynaudio Contour 3.4S with upgraded Esotar 2 tweeters.
2) Match the amp with the speaker. With the Harbeths, I started with Bryston separates (4BSST2 and MP26), then went to an Ayre integrated AX-7E, Luxman 505ux, Hegel H300 and auditioned a friend's Devialet 400. The Bryston separates were great, the Ayre was wimpy, the Hegel okay, the Devialet was great, and I'm keeping the Luxman.
3) Why the Luxman? Bulletproof, excellent sonics, nice features like a loudness button (you'll be listening at low volumes in your home office and it makes a big and pleasant difference). Nice looking and a hefty 60 lbs of Japanese goodness.
4) If this is your work and listening environment, you might consider incorporating a streamer than allows you to install Roon. Roon has an amazing AI interface that will create your own customized listening experience and allow integration with Tidal.

Final thoughts--Luxman has an entire range. The 505ux is excellent and drives the Dyaudios really well, but you can also go Class A in their lineup. A bargain choice is also the Hegel H200 which you can find used for about $2000.

Austin Bob,

I have been a Luxman fan for years.  I can't bring myself to sell my L-590AX!  It's signing away in my office!

I sold luxman for yrs . They always worked great , many of my friends are still rockin 20 yr old luxman gear from me including dd tt

@austinbob -- ditto on the 'match the amp with the speaker' comment.  But I wonder how one decides where to start if not auditioning in pairs.  I recently upgraded to B&W 80s D2s (when learned no longer produced).  Paired with Ayre AX5Twenty integrated due to recommendation by dealer and great reviews.  Horrible combination.  Bright abrasive highs, no bottom end.  Was it the amp or the speakers?  Decided to substitute PASS INT-250 and the results are ideal -- detail, warmth, broad and deep imaging.

@aardvarkbark, good move on the INT-250. The pass has tube-like sweetness. warmth & a forgiving top end, along with the control to get the best out of the D2's which still have a brightish top end. For the same reason I think Vitus would work well with those speakers.