Then the cables should be "burnt-in" for a period of one month. the test repeated and then reversed and "burnt-in" again for the same period and a third test performed using the same identical set-up.
If the result is 2/3-1/3 or more in favor of one direction it would be a statistically significantly proven fact that inherent cable directionality is indeed relevant…
Personally I have never noticed any difference when turning a symmetrically terminated interconnect cable around but that is of course no proof that directionality do not indeed exist in some cases.
The current flow in unbalanced IC's is negligible. Input impedances are in the order of 5-100Kohms so it's basically only voltage changes that are relevant. Speaker cables are a different thing. When powering speakers current is the major factor (except for electrostatic loudspeakers).
Maxwells equations are of course still relevant in IC's but I must say that some people do make some very uneducated scientific remarks in this discussion.
There are basically the following factors:
1. Voltage
2. Current
3. Resistance
4. Capacitance
5. Inductance
6. Impurities in the material
7. Self induction
Factors that are all statistically the same for the whole length of a cable so where does inherent directionality fit in?
I'm not saying that inherent directionality does not exist but until someone presents a double blind test along the lines of the test suggested above I'm very sceptical about it's existence since it does not make any sense at all theoretically. Even if you turn the cable around the strands are still twisted the same way and every other factor also remains the same.
Could it be that the extrusion process would impart an inherit direction? Not very likely since atoms are 100% symmetrical and identical and all impurities in the material are distributed completely at random. The whole concept of inherent directionality in cables just does not make any sense to me as a scientist and if it really does exist it must be possible to scientifically explain the reasons for it.
Can someone please do THAT? Not just present a lot of hocus-pocus statements that have no scientific relevance at all...