There is a fine line between between the quality of the components of a system and the listening capacity of the owner on the one hand (in relation with the mechanical grid,acoustic grid, electrical grid, information grid of his actual listening room) and on the other hand his final hability to discern what need to be implemented first and foremost...
But Geoff is right, in a good system in general tweaks are more easy to discern in their impact and value...But for example if your room is bad, even if your system is good you will not perceive so clearly good tweaks and the so called "snake-oil" and the placebo effects... Conclusion : some tweaks are more important than other to implement first...
For example put resonators even relatively bad one in a room and you will hear clearly evident change, great one or bad one, it is necessary to finetune the resonators for sure to make than very good...My experiment with stones and crystals were great tweaks with positive results but less evident one by one than with the resonators...My tweaking of mechanical vibrations were also evident but less so than the effect of the resonators,but I listen now to my resonators with an already tweaked system, electrically, and mechanically... Without these tweaks perhaps the effect of the resonators would have been there but less astounding in their evidence... All tweaks put my already good system to another level that is for sure...