So far, I've only heard a couple of single driver systems that I could easily live with myself. One is the Voxativ Ampeggio, the other is the Charney Audio system. I particularly like the Charney. I've heard their speaker with the AER and Voxativ driver, and I particularly like the AER driver (a little bit more extended on top, and very smooth).
When "full-range" drivers are coupled with other drivers in multi-way systems, the result can be really good. I've heard some amazingly good systems that use full-range drivers as the bass/midrange driver in two way systems, and I've also heard them used as midrange drivers in three way systems. One big advantage of using full range drivers in multi-way systems is that crossovers can be simpler (I heard, and liked, systems where the full range driver is run full range, with a first order high pass filter network on the tweeter-very minimalist crossover).