Do you like your speakers aimed directly at each ear or....

....and I have Vandersteen 5A's.  Straight ahead doesn't work for my system...it closes up the soundstage.   I opened them gradually, until heard a hole in the middle....closed them to fill the whole, but still opened the walls.  They seem to be pointed to the outer ends of each ear.

As others have said, dispersion patterns of all speakers are different.  And in addition, speakers can be designed specifically to be pointed straight ahead, slightly canted in, or oriented directly at you. All you can do is experiment.

Answers will vary according to hobbyist and system. 

The last three speakers I have used sounded best about 6 to 7 feet apart three feet out from their back wall and parallel to the side walls. 14X26 room. 
Chris and the others have great input no two systems will be the same so play around and listen. Costs nothing!