Uptone EtherRegen

Yes, it did alter the sound, just not in a direction I liked.  But again, I was only one in three (at the time) to return it, so I'm definitely in the minority.

If you want dead quiet streaming, go with a fiber network provider. If you have a copper internet provider, you can clean up the signal to your computer/streamer by using the Ethernet-to-fiber converter then the fiber-to-Ethernet converter for much cheaper with the same benefits. 
For me, I don’t have the computer in the audio room and I use the network interface on my dac, so if I didn’t have my 1G fiber network, I would use this Ethernet-to-fiber conversion technique in front of the dac

Sent mine back today as in my system the sound became  forced, bright, more glare, upper mids were too lively.  After 72 hours I had to remove it and I found my ears were at ease again. I know others had great results, but I guess my system does not play well with it. 

Mojo Audio Evo maxed out 
Innuos Zenith 3 with upgrades
Sabon ethernet cables 

Just my experience. 

I just purchased one today so it will be interesting to try it out; hopefully I'll get it in a couple of days.   

My switch supports both fiber and copper so I'll start out with the copper cable and then jump to the fiber to see if I hear any difference between the two, along with the primary comparison relative to my switch straight to my streamer.  Adding an extra box isn't ideal, but I like the idea in theory at least of decoupling my noisy equipment (NAS, NUC running Roon, switch, etc.) from the input of my streamer (which along with the rest of my audio system is on a dedicated AC line.  Anyhow, time will tell...

I've been using a Regen since August.  It's in series between a SOtM-modified hub and a SOtM trifecta into an Esoteric K-01X, all synchronized to a 10mhz rubidium clock.  In my application the Regen improves things, extending LF authority and adding warmth and suppleness to the midrange and treble.  No brittleness. The outboard clock and a Zerozone 9V linear PS are worthwhile improvements.

The only thing I don't like about the Regen is that it periodically hangs and needs to be rebooted, particularly when the network server is initially powered up.