Mogami 2921 Bi wire vs Canare 4S11 Bi wire Opinions

Can't help you because I have not used the Mogami speaker cables, only the Canare.  While I am not using them at the present time, a search here will find that a number of users believe the Canare is a good not uber expensive cable.

I have only used the Mogami 3104, but I doubt it would be much of a change.
(either seems like a solid choice.)

I use the wire in the 1-3 configuration rather than the 1-2, only be cause the capacitance is touch lower.
Does it matter? Probably not with short monoblock wiring, but maybe with a longer stereo amp… probably not much though.

https://mogamicable.com/category/bulk/speaker_cable/conventional_configuration/

Probably no noticeable difference in the sound of the two types of cables but if you are running the cables internally bi-wired using only one cable per side you may hear improvement by using two separate cables (i.e., more copper) per side.  Here is a termination method for the Mogami wire.

You “might” also hear a difference using a solid core wire, which you can try inexpensively as described here.

Canare 4s11 is a good cable. But as everyone said it’s unlikely to be drastically different than Mogami. 
If you’re looking to build a nice pair of speaker cables give Neotech cable a try. 
Yes it’s more expensive but it will give a lot of bang for your buck.  

Thanks everyone.

I thought there would be little difference but wanted some opinions. My speaker wire has no terminations so I may try to put some on. I like locking Banana connectors. 

I do think the Morrow Audio IC's of solid core wire made a difference. Better in the midrange and bass.