Differences between the sound of USB and AES/BNC/ SP/DIF are fundimentslly different. The USB output is packetized info going to your DAC is a completely different format and will rely on additional processing (including retiming of the bitstream) before converting to analog. While the others only use the basic functions of the DAC. So, the difference between the two can often be thought of as: if my DAC is better than my streamer then most likely the USB will sound better, but if my streamer is better than my DAC, then more likely the other digital formats will sound better. While you have to try it to make sure they very different processing routes.
Non-USB connectors are the same feed coming out different connectors.