Your cabinet thickness on most sides should yield quite an inert structure. The No-Rez is probably the best material to use for the CDL layer. I wanted to experiment with the Polyurethane because it was easily sourced at local Box stores. I applied it to the outside of the inner panels by troweling to about 1mm thickness and then securing the outer box (1/2 solid panels). Don't skimp on the internal bracing side to side as well as tying the center brace to the top and bottom panels.
1) Vocals are really the strong suit of this speaker. They sound very much like the singer is present for both male and female. They raised the perceived level in space of the singer to a higher point in the room as if you are seated and the singer is higher than you on a stage. Almost an eerie sensation because they are there in the room with you! There really is no weakness, but they are darker (because of the warmer midrange) than my Dali Helicon's. Make sure you give plenty of break-in time before you evaluate the sound as they will improve over several weeks of use!
2) Outer cabinet is 11Wx19Hx15D so 1.5CF I was told to not count the bracing in your calculation.
3) I purchased Pangea DS400 20" stands. Perfect for my seating position.
Good Luck. I think you will be quite happy. What speakers do you have now?