What say you binding posts or direct wire?

Perhaps someone will inform my why any form of connection isn't fine as long has it has non-oxidising large contact areas and can be tightened good and tight....

I don't see why the topology should have any effect.

It might be argued that some systems are easier to work with but none of them takes more than a few minutes to connect.

For many many years I just rant bare wire connections from my amp to speakers. I just switched to a very neat array of banana plugs. When I installed the banana plugs I noticed the tarnish, grime whatever on the ends if the wires and what a mess it all looked. Now, I can say I noticed a big improvement in sound. My amp seems to put out more power that I can see on my meters, more definition, more high end etc etc. Perhaps the old connections needed the cleaning and retiring but I am more please with the banana plug connections. All looks neat clean and sounds better. That’s a win for me.

@johnk 
I must be  missing something, if you don’t have a binding post of some kind, how do you connect your speaker wires? You are not suggesting soldering your speaker wires inside your amp?

Anyone tried GR Research Electra tube connectors that Danny touts?  I use Parts Express BPs on my DIY speakers and Madisound’s 15 ga Swedish wire for all internals and solder everything except at the driver terminals, where it’s  crimp connections. Am I potentially suffering FOMO?

Referring to binding posts on speakers. But if one wants I could see where a soldered connection no posts on an amp would most likely be an improvement it would just be a bit impractical to have to desolder amp from speaker to move it. A directly wired speaker is easy to move just roll up the cable. I can see where most couldn't explore a no-posts direct wired speaker but if you DIY a speaker it's a great option to explore. I tend to use fairly high-quality wire when I do so and keep it all the same and eliminate the many extra connections BP requires.