Yes, I've seen (heard) it happen many times. This is why I've always loved the Epi 100 speakers, and love them even more now that they're updated with Human Speakers parts. Rarely... rarely indeed... in 45 years have I heard any speakers that I'd rather have in my home for practical application: dispersive, tight, clear, non-fatiguing, not big size, not picky about placement.
I'm on the hunt, I suppose... trying out the Klipsch Heresy IV currently, but so far I don't see them supplanting the Epi's linearity and beauty. Heresy is a different experience, but not "better" to my ears. I'm looking at maybe the Polk R700, perhaps. But really, Epi - Human Speakers does everything, the best nice tweeter, including bass... maybe a modest sub I suppose, svs micro 3000 or something, but otherwise...
Human Speakers website makes original HS speakers too, one by one... Model 81, as it says in the description, is likely all the speaker most people will ever need. But of course you can use their parts and mod other cabinets, whether it be older Epi or Genesis, or one clever idea is to pop the Human woofer and tweeter into a pair of old Advent Prodigy and voila a small tower speaker that'll rival much, much more expensive speakers.