Do speaker cables really make a difference ?

Back in the day we used a lavadero wash / rinse tub and clothesline … everybody complained. Likely why they didn’t bother to bathe often and wore the same damn clothes for days ;-)

Depending on your system, YES. My garage system is an old boom box with inputs and a removable powercord, but I doubt I’d notice much difference changing the PC.

Back in the days of yore everybody used lamp cord - and nobody complained!

Back in the day we used carrier horse & pigeons for transport and nobody complained.....

@thyname

Touché

They do make difference, but if compared 10k Nordost with lamp cord, you really wouldn't know what sounds better if blind A/B. 

Try doing a blind A/B with 100 of your favorite recordings and you may hear a difference.