Do speaker cables really make a difference ?

Thanks for all the responses. I am thinking about trying Anti Cables speaker wire. It's very thin wire and unless they made the reviews up themselves, they are highly thought of by different users. Any thoughts on Anti Cables ?

Thanks!

When I got Magneplanar MG3s 38 years ago I replaced the 10 gauge Monster Cable (zip cord on steroids) with FMS 1810, much less copper, but designed with multiple thin solid core conductors like AQ, and these were 20+ foot runs. The increase in clarity heard through the ribbons was not subtle. Clearest case I ever heard for the audibility of cable changes. I now have Cardas Cygnus, Transparent Music Wave and Nordost Purple Flare all under 10 feet.  I’m using the Cardas but my hearing isn’t so good anymore. 

When you skimp on cables you loose the potential signal quality delivering the music .

Not trying to be snarky, but genuinely curious, for anyone who might know the answer why:

Spending time in recording studios, ADR stages, and theatrical mixing stages, there are no exotic high-end cables being used (that I’ve seen.) No cables from any of the hifi brand names we all know. There are multi thousand dollar microphones, hundreds of thousands in servers, processing, mixing consoles, etc. But mic cables, interconnects, patch cables, speaker cables, power cables, etc., all of the cabling at these facilities (that I’ve seen) is utilitarian, standard issue recording industry brands. (The facilities are some of the best and most used in the world for music recording/mixing and movie/television postproduction.)

As someone who has owned expensive hifi cables, I wonder why a playback system somehow requires better more expensive cables than the very system where the source material was originally captured and mixed.

Why bother....