You need to be able to control the rolloff of the main speakers. You cant do that by just plugging the port. Some woofers dont work well in sealed boxes. What you really want is a high pass filter. That will enable you to tune the rolloff point and slope so that it integrates with the sub. And it will also prevent any issues with excursion below port tuning frequency. If you follow eriks advice, you will end up stressing the driver cone as all you are doing is causing the driver to be pushed against the air pressure in the box and stressing it.
On the other hand if you dont listen to heavy bass music then it doesnt reallly matter whether you plug the port or not.