Seems there’s some confusion over what bi-amping entails. Two amps, yes, but configured how? There’s passive bi-amping, and then there’s active bi-amping - the latter goes without saying, because you need more amp channels running speakers actively. Run passively, bi-amping (or tri-amping, etc.) is an option when the driver sections have separate terminals that could also be used for bi-wiring (or tri-wiring, etc.). Outboard active configuration is often just (insufficiently, if you ask me) referred to as "bi-amping" when a pair of stereo amps is necessitated to run two driver sections per channel, but in this case we’re dealing with a passive scenario, and so merely ’bi-amping’ would seem a prudent description.
Actively or passively, bi-amping with a pair of similar stereo amps offers the opportunity to go with either a horizontal or vertical configuration. In the passive scenario however, i.e.: with only two stereo amps, there’s a third option: bridged mode. Generally not well regarded in audiophile circles bridging amps can nonetheless be a clear winner sonically, and one will only be the wiser trying it out in the specific case. Which I would here with a pair of A23+ amps, even going so far to say it’d be my preferred scenario (vs. bi-amping horizontally or vertically) comparing it against a single A21+. Place each a23+ close to their speaker, run a single pair of short speaker wires per channel (and longer XLR IC’s), and see how that fares next to a single A21+ with longer speaker wires - if such a comparison is even possible. Just going by a hunch I’d put my money on the dual, bridged A23+ combo (and with the Paradigm’s being regarded as an 8 ohm load, that shouldn’t be an issue), but that’s just me.
Technically I’m tri-amping actively in my own setup, and while a bridged configuration here would be a tempting solution it’d necessitate six(!) stereo amps, which is simply out of the question. As is I prefer running the two stereo amps feeding the mains in a vertical config., and the remaining third amp for the subs as it can only be configured here: horizontally.